FRONTLINE Plus is a trusted monthly topical treatment formulated for large dogs weighing 45 to 88 lbs. This 6-dose pack helps protect against fleas (adults, eggs, larvae), ticks, and chewing lice, delivering durable protection in a single application each month.
Key Benefits & Features
Comprehensive parasite protection — kills adult fleas, flea eggs, larvae, ticks, and lice
Water-resistant, maintaining efficacy after bathing or moisture exposure
Monthly, single-dose application for convenience
Specially formulated for large dogs (45–88 lbs)
Six doses included — good for six months of continuous protection
Ingredients / Active Compounds
| Active Ingredient |
Function |
| Fipronil |
Kills adult fleas and ticks |
| (S)-methoprene |
Prevents development of flea eggs & larvae |
Additional inert ingredients support delivery, absorption, and skin compatibility.
How to Use
1. Ensure the dog is at least 8 weeks old and within the 45–88 lbs weight range.
2. Use one pipette per month — do not exceed one dose in 30 days.
3. Part the dog’s fur at the base of the neck and apply the entire contents of the pipette directly to the skin.
4. Avoid contact with the treated area until dry.
5. Repeat monthly for sustained protection.
Safety & Warnings
For external use only
Use only on dogs in the specified weight range
Do not apply more than one dose per month
If the dog licks the treated area excessively, or shows a skin reaction, wash the area and contact your vet
Avoid contact with eyes; flush thoroughly if accidental exposure occurs
Keep out of reach of children
Store in a cool, dry place, away from sunlight
