Thorne Methyl-Guard Plus is a premium supplement designed to support optimal methylation pathways, promote healthy homocysteine levels, and support overall cellular and cardiovascular health. It combines active forms of folate and B-vitamins with methyl donors for enhanced absorption and efficacy. Thorne+2Mayo Clinic Store+2
This formulation is particularly beneficial for individuals who want targeted support of methylation (e.g. with MTHFR gene variants) while avoiding inactive or synthetic vitamin forms.
Key Benefits & Features
Supports healthy methylation pathways and metabolic function Thorne
Helps maintain balanced homocysteine levels, contributing to cardiovascular and cognitive support Mayo Clinic Store+2Thorne+2
Contains active folate (L-5-MTHF) and tissue-ready forms of vitamins B2, B6, B12 for better utilization Amazon+1
Includes trimethylglycine (betaine) as a methyl donor cofactor Mayo Clinic Store+1
Free from gluten, dairy, soy, eggs, and common allergens Amazon+1
Manufactured under high quality and GMP standards Thorne+1
Ingredients / Supplement Facts
| Component |
Amount per Serving* |
| Betaine (Trimethylglycine) |
~1,800 mg Amazon+1
|
| Folate (as L-5-MTHF) |
~3 mg Amazon+1
|
| Vitamin B12 (Methylcobalamin) |
~3 mg Amazon+1
|
| Vitamin B6 (as P-5-P) |
~45 mg Amazon+1
|
| Vitamin B2 (as Riboflavin 5’-Phosphate) |
~90 mg Amazon+2Thorne+2
|
| Other Ingredients |
Capsule (hypromellose), calcium citrate, calcium laurate, etc. Amazon+1
|
* Serving size is 3 capsules daily, unless otherwise directed by a healthcare professional. Mayo Clinic Store+1
Suggested Use
Take 3 capsules daily with food, or as directed by your healthcare provider. For optimal results, use consistently over time and maintain a healthy lifestyle (diet, hydration, sleep, etc.).
Safety & Precautions
If you are pregnant, nursing, taking medications (especially for cardiovascular, mood, or metabolic health), or have medical conditions, consult a physician before use
Do not exceed the recommended dosage
Discontinue use if any adverse effects occur
Keep out of reach of children
Store in a cool, dry place, away from direct sunlight
